 | Ansen Suites Hotel Istanbul | Boutique | 10 | New City |
 | Antea Hotel Istanbul | Boutique | 42 | Old City |
 | Anthemis Hotel Istanbul | Boutique | 24 | Old City |
 | Antik Hotel istanbul Istanbul | 4.0 star rating | 96 | Old City |
| Antique House Istanbul Hotel | Guest House | 8 | Ataturk Airport Istanbul |
 | Antis Hotel Special Class Istanbul | Boutique | 25 | Old City |
 | Antusa Palace &Spa Hotel Istanbul | 4.0 star rating | 27 | Old City |
 | A Plus Residence Hotel Istanbul | 3.0 star rating | 13 | Old City |
 | Apple Tree Hotel Istanbul | 3.0 star rating | 17 | Old City |
| Aprilis Gold Hotel Istanbul | 4.0 star rating | | Fatih |
 | Aprilis Hotel Istanbul | Boutique | 31 | Old City |
 | Aquarium Hotel Istanbul | Boutique | 21 | Old City |
 | Arach Hotels Harbiye Istanbul | Bed And Breakfast 3* | 19 | New City |
 | Ararat - Haydar Sarigul Hotel Istanbul | 3.0 star rating | 12 | Old City |
 | Arasta Boutique Hotel Istanbul | Boutique | 7 | Old City |
 | Arcade Hotel Istanbul | 5.0 star rating | 51 | New City |
 | Arcadia Blue Istanbul Hotel | 4.0 star rating | 54 | Old City |
| Arca Suite Hotel Istanbul | 4.0 star rating | 42 | Asian Side |
 | Arden City Hotel Istanbul | 3.0 star rating | 36 | Old City |
 | Arden Park Hotel Istanbul | Boutique | 24 | Old City |
 | Arena Hotel Istanbul | Boutique | 27 | Old City |
 | Aren Suites Hotel Istanbul | Boutique | 17 | Old City |
| Ares Hotel Istanbul | 3.0 star rating | 19 | Old City |
 | Aretias Antique House Hotel Istanbul | Aparthotel 2* | 14 | New City |
 | Aretias Suit Home Hotel Istanbul | Aparthotel 3* | 14 | New City |
 | Aristocrat Hotel Istanbul | Boutique | 17 | Old City |
 | Arkem 1 Hotel Istanbul | 3 Keys | 33 | Asian Side |
| Arkem 2 Hotel Istanbul | 3 Keys | | Asian Side |
 | Armada Hotel Old City Sultanahmet Istanbul | 4.0 star rating | 108 | Old City |
 | Armada Istanbul Pera Hotel | Boutique | 20 | New City |
 | Armagrandi Spina Hotel Istanbul | Boutique | 30 | Old City |
 | Arsima Hotel Istanbul | 3.0 star rating | 35 | New City |
 | Art City Hotel Istanbul | 3.0 star rating | 16 | Old City |
 | Art Deco Suites Istanbul Hotel | 4.0 star rating | 30 | New City |
 | Artefes Hotel Istanbul | Boutique | 25 | Old City |
| Artemis Marin Princess Hotel Istanbul | 3.0 star rating | 357 | Ataturk Airport Istanbul |
 | Arts Hotel Istanbul Bosphorus | 5.0 star rating | 100 | New City |
 | Aruna Hotel Istanbul | 4.0 star rating | | Old City |
| Arven Boutique Hotel Istanbul | Boutique | | Sultanahmet |
 | Arx Suites Karakoy Hotel Istanbul | Boutique | 6 | New City |
| Ascot Hotel Istanbul | 4.0 star rating | 22 | Asian Side |
 | As Hotel Beyoglu Istanbul | 2.0 star rating | | New City |
 | As Hotel Taksim Istanbul | 2.0 star rating | 34 | New City |
 | Asia Artemis Hotel Istanbul | 3.0 star rating | 50 | Asian Side |
 | Asia City Hotel Istanbul | 4.0 star rating | 86 | Asian Side |
 | Asia Princess Hotel Istanbul | 4.0 star rating | 110 | Asian Side |
 | Asia Royal Suite Hotel Istanbul | Boutique | 12 | Asian Side |
 | Asitane Life Hotel Istanbul | 3.0 star rating | 12 | Old City |
 | Askin Hotel Istanbul | 3.0 star rating | 19 | Old City |
 | Askoc Hotel Istanbul | 4.0 star rating | 108 | Old City |