 | My Home Sultanahmet Hotel Istanbul | 3.0 star rating | 15 | Old City |
 | Nabu Hotel Karakoy Istanbul | Boutique | 30 | Old City |
 | Nanda Hotel Istanbul | 4.0 star rating | 56 | Old City |
 | Nena Hotel Istanbul | 4.0 star rating | 29 | Old City |
 | Neorion Hotel Istanbul | Boutique | 58 | Old City |
| New Fatih Hotel Istanbul | 3.0 star rating | | Old City |
 | Newport Hotel Istanbul | 3.0 star rating | 44 | Old City |
| Newport Sultanahmet Hotel Istanbul | 3.0 star rating | 23 | Old City |
 | Nidya Hotel Galataport Istanbul | 4.0 star rating | 90 | Old City |
 | Noahs Ark Hotel Istanbul | Boutique | 18 | Old City |
 | Nobel Hotel Istanbul | 3.0 star rating | 30 | Old City |
 | Noble22 Suites Hotel Istanbul | 3.0 star rating | 22 | Old City |
| Nomade Hotel Istanbul | 3.0 star rating | 16 | Old City |
 | Nordstern Hotel Galata Istanbul | Boutique | 18 | Old City |
 | Novotel Istanbul Bosphorus Hotel | 5.0 star rating | 200 | Old City |
 | Nowy Efendi Hotel Istanbul | Boutique | 28 | Old City |
 | Oban Suites Istanbul Hotel | Boutique | 13 | Old City |
| Oceans 7 Hotel Istanbul | Standard | 15 | Old City |
 | Old City Family Hotel Istanbul | Boutique | 14 | Old City |
 | Old Panorama Hotel Istanbul | Boutique | 14 | Old City |
 | Olimpiyat Hotel Istanbul | 3.0 star rating | 59 | Old City |
 | Oran Hotel Istanbul | 4.0 star rating | 89 | Old City |
 | Orient Express Hotel Istanbul | 4.0 star rating | 52 | Old City |
 | Orient Mintur Hotel Istanbul | 3.0 star rating | 43 | Old City |
 | Orka Royal Hotel Istanbul | 4.0 star rating | 117 | Old City |
 | Ottoman Elegance Hotel Istanbul | 3.0 star rating | 22 | Old City |
| Ottoman Hotel Cagaloglu Istanbul | Boutique | 34 | Old City |
 | Ottoman Hotel Imperial Istanbul | Boutique | 49 | Old City |
 | Ottoman Hotel Park Istanbul | Boutique | 38 | Old City |
 | Ottoman Luxury Hotel Istanbul | 3.0 star rating | 12 | Old City |
 | Ottomans Life Hotel Istanbul | Boutique | 32 | Old City |
 | Ottoman Tulip Hotel Istanbul | Boutique | 14 | Old City |
| Parkhouse Hotel & Spa Istanbul | 4.0 star rating | 30 | Old City |
 | Parmada Hotel Old City Istanbul | Boutique | 24 | Old City |
 | Peninsula Galata Boutique Hotel Istanbul | Boutique | 31 | Old City |
 | Pera Apartmenthotel Hotel Istanbul | Aparthotel 3* | 9 | Old City |
 | Perula Hotel Istanbul | 4.0 star rating | 30 | Old City |
| Peyk Hotel Istanbul | Boutique | 26 | Old City |
 | Poem Special Hotel Istanbul | 2.0 star rating | 17 | Old City |
 | Polatdemir Hotel Istanbul | 3.0 star rating | 45 | Old City |
 | Premist Hotels Istanbul | Boutique | 31 | Old City |
 | Prestige Hotel Istanbul | 3.0 star rating | 98 | Old City |
| Prime Suites Hotel Istanbul | 5.0 star rating | 116 | Old City |
 | Princess Old City Hotel Istanbul | 4.0 star rating | 72 | Old City |
 | Q Hotel Istanbul | 3.0 star rating | | Old City |
 | Q Inn Hotel Istanbul | 3.0 star rating | 40 | Old City |
 | QInn Hotel Old City Sirkeci Istanbul | 3.0 star rating | 42 | Old City |
 | Ramada Istanbul Grand Bazaar Hotel | 4.0 star rating | 70 | Old City |
 | Ramada Istanbul Old City Hotel | 4.0 star rating | 100 | Old City |
 | Rast Hotel Sultanamet Istanbul | 3.0 star rating | 29 | Old City |