| Holiday Inn Express Mira Mesa-San Diego Hotel San Diego - CA | 3.0 star rating | 70 | North San Diego |
 | Holiday Inn Express-National City Hotel San Diego - CA | 2.0 star rating | 91 | National City |
 | Holiday Inn Express Otay Mesa Hotel San Diego - CA | 3.0 star rating | 99 | Otay Mesa |
 | Holiday Inn Express San Diego Hotel San Diego - CA | 3.0 star rating | | Downtown/Gaslamp District |
 | Holiday Inn Express San Diego Hotel Circle San Diego - CA | 3.0 star rating | 104 | Mission Valley |
 | Holiday Inn Express San Diego- Sea World Hotel San Diego - CA | 3.0 star rating | 71 | Mission Bay-Sea World |
 | Holiday Inn Express San Diego Sea World - Beach Ar Hotel San Diego - CA | 3.0 star rating | 116 | Mission Bay-Sea World |
 | Holiday Inn Express San Diego South - Chula Vista Hotel San Diego - CA | 2.0 star rating | 88 | Chula Vista |
| Holiday Inn Express Temecula Hotel San Diego - CA | 3.0 star rating | 90 | Temecula |
 | Holiday Inn La Mesa Hotel San Diego - CA | 3.0 star rating | 141 | El Cajon - La Mesa |
 | Holiday Inn Oceanside Marina-Camp Pendleton Area Hotel San Diego - CA | 3.0 star rating | 20 | Oceanside |
 | Holiday Inn San Diego-Rancho Bernardo Hotel San Diego - CA | 3.0 star rating | 180 | North San Diego |
 | Holiday Inn Select San Diego North Miramar Hotel San Diego - CA | 3.0 star rating | 155 | North San Diego |
 | Homewood Suites by Hilton Carlsbad-North San Hotel San Diego - CA | 3.0 star rating | 145 | Carlsbad Airport |
 | Homewood Suites by Hilton San Diego Hotel San Diego - CA | 3.0 star rating | 150 | San Diego International Airport |
 | Homewood Suites by Hilton San Diego-Del Mar Hotel San Diego - CA | 3.0 star rating | 120 | Del Mar |
 | Homewood Suites by Hilton San Diego Downtown Hotel San Diego - CA | 3.0 star rating | 160 | Downtown/Gaslamp District |
 | Homewood Suites by Hilton San Diego/Mission Valley Hotel San Diego - CA | 3.0 star rating | 118 | Mission Valley |
| Homewood Suites by Hilton San Diego/SeaWorld Area Hotel San Diego - CA | 3.0 star rating | | Mission Valley |
 | HOTEL AQUA MAR Hotel San Diego - CA | 2.0 star rating | 100 | Downtown/Gaslamp District |
 | Hotel Del Coronado San Diego - CA | 5.0 star rating | 688 | Coronado |
| Hotel Indigo Del Mar San Diego - CA | 3.0 star rating | 93 | Del Mar |
| Hotel Inn At The Park San Diego San Diego - CA | 3.0 star rating | 75 | Hillcrest |
 | Hotel Karlan San Diego A DoubleTree by Hilton San Diego - CA | 4.0 star rating | 174 | La Jolla |
 | Hotel La Jolla San Diego - CA | 3.0 star rating | 110 | La Jolla |
 | Hotel Point Loma San Diego - CA | 1 Star | 14 | San Diego International Airport |
 | Howard Johnson Express Inn National City/San Diego Hotel San Diego - CA | 2.0 star rating | 65 | National City |
 | Howard Johnson Inn and Suites Hotel San Diego - CA | 2.0 star rating | 85 | Chula Vista |
 | Howard Johnson Inn San Diego Hotel Circle San Diego - CA | 2.0 star rating | 80 | Mission Valley |
 | Howard Johnson Inn - San Diego Sea World Hotel San Diego - CA | 2.0 star rating | 98 | Mission Bay-Sea World |
 | Howard Johnson Inn San Diego State University Area Hotel San Diego - CA | 3.0 star rating | 50 | El Cajon - La Mesa |
 | Humphrey's Half Moon Inn Hotel San Diego - CA | 3.0 star rating | 182 | Shelter Island |
| HYATT house San Diego/Carlsbad Hotel San Diego - CA | 3.0 star rating | | Carlsbad - Oceanside |
| HYATT house San Diego/Sorrento Mesa Hotel San Diego - CA | 3.0 star rating | 193 | North San Diego |
| HYATT PLACE SAN DIEGO VISTA CARLSBA Hotel San Diego - CA | 3.0 star rating | | Carlsbad Airport |
 | Hyatt Regency La Jolla At Aventine Hotel San Diego - CA | 4.0 star rating | 417 | La Jolla |
 | Hyatt Regency Mission Bay Spa & Marina Hotel San Diego - CA | 4.0 star rating | 429 | Mission Bay-Sea World |
 | Indigo - San Diego Gaslamp Quarter Hotel San Diego - CA | 4.0 star rating | 210 | Downtown/Gaslamp District |
| Inn at the Park Hotel San Diego - CA | 3.0 star rating | 82 | Downtown/Gaslamp District |
 | Inn by the Sea at la Jolla Hotel San Diego - CA | 3.0 star rating | 129 | La Jolla |
 | Knights Inn San Ysidro Hotel San Diego - CA | 3.0 star rating | 115 | San Ysidro |
 | Kona Kai Resort and Spa San Diego - CA | 4.0 star rating | 129 | Shelter Island |
| Lafayette Hotel San Diego - CA | 3.0 star rating | 131 | Mission Valley |
 | La Jolla Beach and Tennis Club Hotel San Diego - CA | 3.0 star rating | 98 | La Jolla |
 | La Jolla Beach Travelodge Hotel San Diego - CA | 4.0 star rating | 44 | La Jolla |
 | La Jolla Cove Suites Hotel San Diego - CA | 3.0 star rating | 110 | La Jolla |
| Lakehouse Hotel and Resort San Diego - CA | 4.0 star rating | 142 | San Marcos area |
 | La Quinta Inn Carlsbad Hotel San Diego - CA | 3.0 star rating | 110 | Carlsbad - Oceanside |
 | La Quinta Inn Old Town Hotel San Diego - CA | 3.0 star rating | 79 | Old Town |
 | La Quinta Inn San Diego Rancho Scripps Poway Hotel San Diego - CA | 3.0 star rating | 120 | Poway |