 | La Rovere Hotel Rome | 4.0 star rating | 20 | Vaticano |
 | La Vite Vaticana Hotel Rome | Guest House | 5 | Vaticano |
 | Le Meridien Visconti Rome Hotel | 4.0 star rating | 240 | Vaticano |
 | Lemon Garden Hotel Rome | 3.0 star rating | 17 | Vaticano |
 | Le Suite Di Via Ottaviano B&B Hotel Rome | Bed And Breakfast | 5 | Vaticano |
 | Lt Rooms Hotel Rome | Bed And Breakfast | 6 | Vaticano |
 | Luxury on the River Hotel Rome | 3.0 star rating | 6 | Vaticano |
 | Luxury on the River Hotel Rome | Bed And Breakfast | 6 | Vaticano |
 | Maison Genevois 3 B&B Hotel Rome | Bed And Breakfast | 3 | Vaticano |
 | Mdm Luxury Rooms Guest House Hotel Rome | Guest House | 10 | Vaticano |
 | Metropolis Hotel Rome | 4.0 star rating | 55 | Vaticano |
 | Nautilus Hotel Rome | 3.0 star rating | 11 | Vaticano |
 | Next Stop St Peter Hotel Rome | Apartment 1st Category | 3 | Vaticano |
 | NH Collection Roma Giustiniano Hotel Rome | 4.0 star rating | 161 | Vaticano |
 | NH Roma Leonardo da Vinci Hotel Rome | 4.0 star rating | 261 | Vaticano |
| Old Kitchen B&B Hotel Rome | Bed And Breakfast | 4 | Vaticano |
| Opera Street In Vatican Hotel Rome | Guest House | | Vaticano |
 | Orange Hotel Rome | 4.0 star rating | 28 | Vaticano |
 | Ottaviano Holiday House Hotel Rome | Bed And Breakfast | 6 | Vaticano |
 | Pacific Hotel Rome | 3.0 star rating | 80 | Vaticano |
 | Palazzo Cardinal Cesi Hotel Rome | 4.0 star rating | 30 | Vaticano |
| Palazzo Dama Hotel Rome | 5.0 star rating | | Vaticano |
 | PapavistaRelais Hotel Rome | 3.0 star rating | 6 | Vaticano |
| Pensione Paradise Hotel Rome | 3.0 star rating | 10 | Vaticano |
 | Piazza Navona Large Panoramic - Four Bedroom Hotel Rome | Without Official Category | | Vaticano |
 | Popolo Apartment - Three Bedroom Hotel Rome | Without Official Category | | Vaticano |
 | Pratinn Vatican Hotel Rome | Bed And Breakfast | 4 | Vaticano |
| Quality Hotel Nova Domus Rome | 4.0 star rating | 122 | Vaticano |
 | Quiriti Hotel Rome | 2.0 star rating | 10 | Vaticano |
| Quo Vadis Roma Hotel Rome | Bed And Breakfast | 3 | Vaticano |
| Quo Vadis Roma 2 Hotel Rome | Bed And Breakfast | 4 | Vaticano |
 | Regina'S House - St Peter - Two Bedroom Hotel Rome | Without Official Category | | Vaticano |
| Relais Dei Papi Hotel Rome | 3.0 star rating | 29 | Vaticano |
| Relais Group Palace Hotel Rome | 3.0 star rating | 10 | Vaticano |
 | Relais San Pietro Hotel Rome | Guest House | 6 | Vaticano |
 | Relais Vaticano Hotel Rome | 3.0 star rating | 1 | Vaticano |
 | Residence Candia Hotel Rome | 3.0 star rating | 75 | Vaticano |
 | Residence Prati Hotel Rome | 3.0 star rating | 38 | Vaticano |
 | Residence Trianon Borgo Pio Hotel Rome | Residence | 45 | Vaticano |
 | Residenza Cavallini Hotel Rome | Guest House | 6 | Vaticano |
 | Residenza Cola Di Rienzo - Suite in Rome Hotel | Bed And Breakfast | 6 | Vaticano |
 | Residenza Dei Gracchi Hotel Rome | Bed And Breakfast | 4 | Vaticano |
| Residenza I Rioni Guesthouse Hotel Rome | 3.0 star rating | 6 | Vaticano |
 | Residenza Paolo VI Hotel Rome | 4.0 star rating | 35 | Vaticano |
 | Residenza Ponte Sant'Angelo Hotel Rome | 3.0 star rating | 5 | Vaticano |
 | Residenza Risorgimento Hotel Rome | Guest House | 6 | Vaticano |
 | Residenza Roma Hotel Rome | Residence | 7 | Vaticano |
| Ripetta Luxury Hotel Rome | Without Official Category | | Vaticano |
 | Roma Inn Hotel Rome | Bed And Breakfast | | Vaticano |
| Roman Dreams Hotel Rome | 3.0 star rating | | Vaticano |