 | Aloft Greenville Downtown Hotel Spartanburg - Greenville - SC | 3.0 star rating | 144 | Greenville |
| Baymont Inn & Suites Anderson Clemson Hotel Spartanburg - Greenville - SC | 3.0 star rating | 58 | Clemson |
| Baymont Inn & Suites Duncan/Spartanburg Hotel Spartanburg - Greenville - SC | 2.0 star rating | | Duncan |
 | Baymont Inn & Suites Easley/Greenville Hotel Spartanburg - Greenville - SC | 3.0 star rating | 57 | Clemson |
| Baymont Inn & Suites Gaffney Hotel Spartanburg - Greenville - SC | Without Official Category | | Gaffney |
 | Baymont Inn & Suites Greenville Woodruff Rd Hotel Spartanburg - Greenville - SC | 3.0 star rating | 122 | Greenville |
 | Best Western Executive Inn Hotel Spartanburg - Greenville - SC | 3.0 star rating | 58 | Seneca |
 | Best Western Greenville Airport Hotel Spartanburg - Greenville - SC | 2.0 star rating | 141 | Greenville |
 | Best Western Plus Piedmont Inn & Suites Hotel Spartanburg - Greenville - SC | 3.0 star rating | 60 | Spartanburg |
| Best Western Plus University Inn & Conference Ctr Hotel Spartanburg - Greenville - SC | 2.0 star rating | | Clemson |
 | BEST WESTERN Travelers Rest/Greenville Hotel Spartanburg - Greenville - SC | 2.0 star rating | 60 | Greenville |
| Candlewood Suites Greenville Hotel Spartanburg - Greenville - SC | Without Official Category | | Greenville |
 | Clarion Inn & Suites Haywood Mall Area Hotel Spartanburg - Greenville - SC | 3.0 star rating | 126 | Greenville |
 | Comfort Inn Hotel Spartanburg - Greenville - SC | 2.0 star rating | 122 | Clemson |
 | Comfort Inn (Clinton) Hotel Spartanburg - Greenville - SC | 2.0 star rating | 81 | Clinton |
 | Comfort Inn Millennium Hotel Spartanburg - Greenville - SC | 3.0 star rating | 117 | Greenville |
 | Comfort Inn & Suites Hotel Spartanburg - Greenville - SC | 4.0 star rating | | Clemson |
 | Comfort Inn & Suites Hotel Spartanburg - Greenville - SC | 1 Star | 65 | Spartanburg |
 | Comfort Inn & Suites Hotel Spartanburg - Greenville - SC | 3.0 star rating | 120 | Greenville |
 | Comfort Suites Hotel Spartanburg - Greenville - SC | 3.0 star rating | 76 | Greenville |
 | Comfort Suites Hotel Spartanburg - Greenville - SC | 3.0 star rating | 60 | Greenville |
 | Comfort Suites Hotel Spartanburg - Greenville - SC | 3.0 star rating | 91 | Clinton |
 | Comfort Suites At WestGate Mall Hotel Spartanburg - Greenville - SC | 3.0 star rating | 86 | Spartanburg |
| Comfort Suites Greenville South Hotel Spartanburg - Greenville - SC | Without Official Category | | Clemson |
| Courtyard Clemson Hotel Spartanburg - Greenville - SC | 3.0 star rating | 110 | Clemson |
| Courtyard Greenville Downtown Hotel Spartanburg - Greenville - SC | 3.0 star rating | 297 | Piedmont |
| Courtyard Greenville Haywood Mall Hotel Spartanburg - Greenville - SC | 3.0 star rating | 146 | Piedmont |
| Courtyard Greenville-Spartanburg Airport Hotel Spartanburg - Greenville - SC | 3.0 star rating | 136 | Piedmont |
 | Courtyard Spartanburg Hotel Spartanburg - Greenville - SC | 3.0 star rating | 102 | Spartanburg |
| Crowne Plaza Greenville I 385 Roper Mtn Rd Hotel Spartanburg - Greenville - SC | 4.0 star rating | | Greenville |
 | Days Inn Anderson Hotel Spartanburg - Greenville - SC | 3.0 star rating | 52 | Greenville |
 | Days Inn Clemson Hotel Spartanburg - Greenville - SC | 3.0 star rating | 46 | Clemson |
 | Days Inn Clinton-Presbyterian College Hotel Spartanburg - Greenville - SC | 3.0 star rating | 58 | Clinton |
 | Days Inn Easley West Of Greenville/Clemson Area Hotel Spartanburg - Greenville - SC | 3.0 star rating | 72 | Clemson |
 | Days Inn Greenville Hotel Spartanburg - Greenville - SC | 3.0 star rating | 110 | Greenville |
| Days Inn Mauldin/Greenville Hotel Spartanburg - Greenville - SC | 3.0 star rating | 49 | Greenville |
 | Days Inn Seneca Hotel Spartanburg - Greenville - SC | 3.0 star rating | 63 | Seneca |
 | Days Inn Simpsonville Hotel Spartanburg - Greenville - SC | 3.0 star rating | 38 | Greenville |
 | Days Inn Spartanburg Hotel Spartanburg - Greenville - SC | 3.0 star rating | 42 | Spartanburg |
 | Days Inn Spartanburg, Waccamaw Hotel Spartanburg - Greenville - SC | 3.0 star rating | 82 | Spartanburg |
| Days Inn & Suites Duncan/Spartanburg Hotel Spartanburg - Greenville - SC | 2.0 star rating | | Duncan |
 | Days Inn Union Hotel Spartanburg - Greenville - SC | 3.0 star rating | 36 | Union |
 | Econo Lodge Hotel Spartanburg - Greenville - SC | 1 Star And A Half | 45 | Spartanburg |
 | Econo Lodge Inn & Suites Hotel Spartanburg - Greenville - SC | 1 Star And A Half | 92 | Greenville |
| Embassy Suites by Hilton Greenville Downtown, SC Hotel Spartanburg - Greenville - SC | 3.0 star rating | 156 | Piedmont |
 | Embassy Suites Greenville Golf Resort Spartanburg - Greenville - SC | 3.0 star rating | 268 | Greenville |
| Extended Stay America - Greenville - Airport Hotel Spartanburg - Greenville - SC | 3.0 star rating | 109 | Greenville |
| Extended Stay America - Greenville - Haywood Mall Hotel Spartanburg - Greenville - SC | 3.0 star rating | 72 | Greenville |
 | Fairfield Inn By Marriott Greenville Hotel Spartanburg - Greenville - SC | 3.0 star rating | 94 | Greenville |
| Greenville Marriott Hotel Spartanburg - Greenville - SC | 3.0 star rating | 199 | Piedmont |