 | On the Cliff Guest House Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 8 | Hermanus |
| O on Kloof Hotel W. Cape-Cape Town-Garden Route | 3.0 star rating | 8 | Cape Town |
 | Orange-Ville Guesthouse Hotel W. Cape-Cape Town-Garden Route | 3.0 star rating | 8 | Stellenbosch |
 | Oubaai Hotel Golf and Spa W. Cape-Cape Town-Garden Route | 4.0 star rating | 100 | George |
| Oude Wellington Wine Estate Hotel W. Cape-Cape Town-Garden Route | 3.0 star rating | 9 | Paarl |
 | Oude Werf Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 63 | Stellenbosch |
| Palmiet Valley Estate Hotel W. Cape-Cape Town-Garden Route | 3.0 star rating | 14 | Paarl |
 | Park Inn by Radisson Cape Town Foreshore Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 120 | Cape Town |
 | Park Inn by Radisson Cape Town Newlands Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 122 | Cape Town |
 | Paternoster Cottages Hotel W. Cape-Cape Town-Garden Route | 3.0 star rating | 5 | Paternoster |
| Pearl Valley Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 80 | Paarl |
 | Pepper Club Hotel & SPA W. Cape-Cape Town-Garden Route | 5.0 star rating | 137 | Cape Town |
 | Perna Perna Mossel Bay Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | | Mossel Bay |
| Pezula Resort Hotel & Spa W. Cape-Cape Town-Garden Route | 3.0 star rating | 1 | Knysna |
 | Place on the Bay Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 21 | Cape Town |
 | Plettenberg Park Hotel & Spa W. Cape-Cape Town-Garden Route | 5.0 star rating | 10 | Plettenberg Bay |
 | Port Owen Marina Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | | Velddrif |
 | Premier Hotel Cape Town W. Cape-Cape Town-Garden Route | 4.0 star rating | 99 | Cape Town |
 | Premier Resort- The Moorings, Knysna W. Cape-Cape Town-Garden Route | 4.0 star rating | 63 | Knysna |
 | President Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 349 | Cape Town |
 | Primi Royal Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 10 | Cape Town |
 | Primi Seacastle Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 10 | Cape Town |
 | Protea Cumberland Hotel W. Cape-Cape Town-Garden Route | 3.0 star rating | 55 | Worcester |
 | Protea Hotel by Marriot Cape Town Breakwater Lodge W. Cape-Cape Town-Garden Route | 3.0 star rating | 191 | Cape Town |
 | Protea Hotel by Marriott Franschhoek W. Cape-Cape Town-Garden Route | 4.0 star rating | 30 | Franschhoek |
 | Protea Hotel Cape Castle W. Cape-Cape Town-Garden Route | 3.0 star rating | 67 | Cape Town |
 | Protea Hotel Dorphuis & Spa W. Cape-Cape Town-Garden Route | 4.0 star rating | 88 | Stellenbosch |
 | Protea Hotel Durbanville W. Cape-Cape Town-Garden Route | 3.0 star rating | 95 | Cape Town |
 | Protea Hotel Fire & Ice! Cape Town W. Cape-Cape Town-Garden Route | 4.0 star rating | 201 | Cape Town |
 | Protea Hotel King George W. Cape-Cape Town-Garden Route | 4.0 star rating | 109 | George |
 | Protea Hotel Mossel Bay W. Cape-Cape Town-Garden Route | 4.0 star rating | 31 | Mossel Bay |
 | Protea Hotel Mowbray W. Cape-Cape Town-Garden Route | 3.0 star rating | 70 | Cape Town |
 | Protea Hotel North Wharf W. Cape-Cape Town-Garden Route | 4.0 star rating | 67 | Cape Town |
 | Protea Hotel Outeniqua, George W. Cape-Cape Town-Garden Route | 3.0 star rating | 50 | George |
 | Protea Hotel Riempie Estate W. Cape-Cape Town-Garden Route | 3.0 star rating | 39 | Oudtshoorn |
 | Protea Hotel Saldanha Bay W. Cape-Cape Town-Garden Route | 3.0 star rating | 60 | Saldanha |
 | Protea Hotel Sea Point W. Cape-Cape Town-Garden Route | 3.0 star rating | 124 | Cape Town |
 | Protea Hotel Stellenbosch W. Cape-Cape Town-Garden Route | 3.0 star rating | 180 | Stellenbosch |
 | Protea Knysna Quays Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 123 | Knysna |
 | Protea Tyger Valley Hotel W. Cape-Cape Town-Garden Route | 3.0 star rating | 100 | Cape Town |
 | Protea Victoria Junction Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 172 | Cape Town |
 | Queen's Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 40 | Oudtshoorn |
 | Queen Victoria Hotel W. Cape-Cape Town-Garden Route | 5.0 star rating | 35 | Cape Town |
 | Radisson Blu Hotel & Residence W. Cape-Cape Town-Garden Route | 4.0 star rating | 214 | Cape Town |
 | Radisson Blu Hotel Waterfront W. Cape-Cape Town-Garden Route | 5.0 star rating | 177 | Cape Town |
 | Radisson Blu Le Vendome Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 143 | Cape Town |
 | Radisson Red Cape Town Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 242 | Cape Town |
 | Redbourne Country Lodge Hotel W. Cape-Cape Town-Garden Route | 4.0 star rating | 16 | Plettenberg Bay |
 | Residence Vive La Vie Hotel W. Cape-Cape Town-Garden Route | Bed And Breakfast | 2016 | Franschhoek |
 | RETREAT ON CLIFF Hotel W. Cape-Cape Town-Garden Route | Guest House | 3 | Cape Town |