 | Sandy Beach Hotel Crete | 3.0 star rating | 71 | Georgioupolis |
| Sandy Villas Hotel Crete | Villa | | Aghia Marina |
| Santa Helena Hotel Crete | 4.0 star rating | | Chania-Platanias |
 | Santa Marina Hotel Crete | 3.0 star rating | 198 | Aghios Nikolaos |
 | Santa Marina Beach Hotel Crete | 4.0 star rating | 208 | Amoudara |
 | Santa Marina Beach hotel Hotel Crete | 4.0 star rating | 188 | Aghia Marina |
 | Santa Marina Plaza Hotel Crete | 5.0 star rating | 51 | Aghia Marina |
 | Sarikampos Beach Hotel Crete | 2.0 star rating | 18 | Ierapetra |
 | Scala Hotel Apartments Crete | 4.0 star rating | 20 | Aghia Pelagia |
 | Scaleta Beach Hotel Crete | 3.0 star rating | 31 | Rethymnon |
 | Sea And Landscape Views Near Rethymno At Thea Lats Hotel Crete | Without Official Category | | Rethymnon |
| Sea Breeze Hotel Crete | 3 Keys | 10 | Kalamaki Cre |
 | Sea Breeze Hotel Crete | 2.0 star rating | 25 | Sitia |
 | Sea Front Hotel Crete | 3.0 star rating | 64 | Rethymnon-Adelianos Kampos |
 | Seagull Hotel Crete | 2.0 star rating | 28 | Aghia Marina |
 | Sea Side Resort & Spa Crete | 5.0 star rating | | Aghia Pelagia |
 | Sea View Hotel Crete | 4.0 star rating | 60 | Kolymbari |
 | Sea Views At Anemomylos Villa For Up To 18 People Hotel Crete | Without Official Category | | Aghia Pelagia |
 | Sea Views At Blue Key Villa Near Heraklion. Hotel Crete | Without Official Category | | Aghia Pelagia |
 | Selena Hotel Crete | 3.0 star rating | 72 | Elounda |
| Selena View Hotel Crete | 3.0 star rating | 19 | Malia |
 | Selini Suites Hotel Crete | 4.0 star rating | 112 | Kolymbari |
 | Selini Villas Hotel Crete | 4.0 star rating | 112 | Kolymbari |
 | Semiramis Apartments Hotel Crete | 3.0 star rating | 20 | Malia |
 | Semiramis Apartments Hotel Crete | 3.0 star rating | 11 | Hersonissos |
 | Semiramis Suites Hotel Crete | 2.0 star rating | 11 | ChaniaâChrissi Akti |
 | Semiramis Village Hotel Crete | 4.0 star rating | 190 | Hersonissos |
 | Sensimar Minos Palace Hotel Crete | 5.0 star rating | 148 | Aghios Nikolaos |
| Sensimar Minos Palace Hotel Suites Crete | 5.0 star rating | | Aghios Nikolaos |
 | Sensimar Royal Blue Resort & Spa Crete | 5.0 star rating | 191 | Panormos |
 | Sensumar Elounda Village Resort & Spa Crete | 5.0 star rating | 208 | Elounda |
 | Sentido Aegean Pearl Hotel Crete | 5.0 star rating | 110 | Rethymnon |
| SENTIDO BLUE SEA Hotel Crete | 5.0 star rating | | Heraklion City |
 | Sentido Pearl Beach Hotel Crete | 4.0 star rating | 160 | Rethymnon |
 | Serenissima Boutique Hotel Crete | 5.0 star rating | 7 | Chania City |
| Serenissima Boutique Hotel Crete | 5.0 star rating | | Chania City |
 | Sergios Hotel Crete | 3.0 star rating | 97 | Hersonissos |
 | Serita Beach Hotel Crete | 5.0 star rating | 272 | Anissaras |
 | Sevach Apartments Hotel Crete | 3 Keys | 10 | Kalamaki Cre |
 | Sgouros Hotel Crete | 2.0 star rating | 27 | Aghios Nikolaos |
 | Silva Beach Hotel Crete | 4.0 star rating | 312 | Hersonissos |
| Silver Beach Hotel Crete | 4.0 star rating | 51 | Chania-Platanias |
 | Sirens Beach Hotel Crete | 4.0 star rating | 247 | Malia |
 | Sirios Village Hotel Crete | 4.0 star rating | 140 | Chania-Kato Daratso |
| Sirius Apartments Hotel Crete | 2 Keys | 10 | Hersonissos |
 | Sissi Bay Hotel Crete | 4.0 star rating | 80 | Sissi |
 | Sitia Bay Hotel Crete | 3.0 star rating | 17 | Sitia |
 | Sitia Beach City Resort & Spa Crete | 5.0 star rating | 161 | Sitia |
 | Skajado Apartments Hotel Crete | 3.0 star rating | 10 | Stalis |
 | smartline Dimitrios Beach Hotel Crete | 4.0 star rating | 98 | Rethymnon |