 | Amelie Santorini Hotel | 3.0 star rating | 18 | Kamari |
 | Amerisa Suites Hotel Santorini | 4 Keys | 14 | Fira |
| Amerisa Suites Hotel Santorini | 3.0 star rating | | Messaria |
 | Ampelonas Hotel Santorini | 3 Keys | 14 | Imerovigli |
 | Anassa Hotel Santorini | 4.0 star rating | 17 | Kamari |
 | Anastasia Princess Boutique Hotel Santorini | 4 Keys | 25 | Perissa-Perivolos |
 | Ancient Thera Studios Hotel Santorini | 3 Keys | 16 | Perissa-Perivolos |
 | Andreas Aparthotel Hotel Santorini | 3.0 star rating | 35 | Kamari |
 | Andromeda Villas Hotel Santorini | 4.0 star rating | 58 | Imerovigli |
 | Andronikos Santorini Hotel | 4.0 star rating | 6 | Imerovigli |
 | Andronis Boutique Hotel Santorini | 5.0 star rating | 14 | Oia |
 | Andronis Concept Wellness Resort Santorini | 5.0 star rating | 25 | Imerovigli |
 | Andronis Honeymoon Hotel Santorini | 4.0 star rating | 5 | Fira |
 | Andronis Luxury Suites Hotel Santorini | 5.0 star rating | 22 | Oia |
 | Anemolia Villa Hotel Santorini | Villa | 2 | Megalochori |
| Anemomilos Hotel Santorini | 3.0 star rating | 25 | Oia |
 | Anemones Htl Hotel Santorini | Aparthotel 1* | 20 | Kamari |
 | Anemos beach lounge Hotel Santorini | 4.0 star rating | 30 | Perissa-Perivolos |
 | Anemos Studios Hotel Santorini | 3.0 star rating | 4 | Perissa-Perivolos |
| Anessis Hotel Santorini | 3 Keys | 13 | Fira |
 | Aneta Hotel Santorini | 2.0 star rating | | Kamari |
| Anezina Villas Hotel Santorini | 3.0 star rating | | Perissa-Perivolos |
| Angel In Fira Hotel Santorini | 2.0 star rating | | Perissa-Perivolos |
 | Angels In Fira Hotel Santorini | 3.0 star rating | 15 | Fira |
 | Anna Apartments Hotel Santorini | 2 Keys | 12 | Aghios Paraskevi-Monolithos |
 | Anny Hotel Santorini | 2.0 star rating | 57 | Messaria |
| Anny Studios Perissa Beach Hotel Santorini | 3 Keys | 29 | Perissa-Perivolos |
 | Antinea Hotel Suites and spa Santorini | 4.0 star rating | 46 | Kamari |
| Antinea Suites & Spa Hotel Santorini | 4.0 star rating | 36 | Kamari |
| Antithesis Caldera Cliff Santorini Hotel | 4.0 star rating | 5 | Fira |
 | Apanemo Htl Hotel Santorini | 3.0 star rating | 25 | Akrotiri |
 | Aparthotel Black Sand Hotel Santorini | 3.0 star rating | 18 | Kamari |
 | Aperanto Suites Hotel Santorini | 4.0 star rating | 15 | Kamari |
| Apolafsi Villa Hotel Santorini | 3.0 star rating | | Imerovigli |
 | Aqua Blue Hotel Santorini | 4.0 star rating | 80 | Perissa-Perivolos |
 | Aqua Luxury Suites Hotel Santorini | 5.0 star rating | 11 | Imerovigli |
 | Archontiko Santorini Hotel | 1 Star | 3 | Fira |
 | Aressana Spa Hotel & Suites Santorini | 5.0 star rating | 48 | Fira |
 | Aria Lito Mansion Hotel Santorini | 4 Keys | 15 | Fira |
 | Aria Suites Hotel Santorini | 4.0 star rating | 6 | Fira |
 | Arion Bay Hotel Santorini | 1 Star | 42 | Kamari |
 | Armeni Village Hotel Santorini | Aparthotel 4* | 12 | Oia |
 | Armeni Villas Hotel Santorini | 5.0 star rating | 3 | Oia |
| Aroma Suites Hotel Santorini | 3.0 star rating | 7 | Fira |
 | Artemis Santorini Hotel | 3.0 star rating | 35 | Kamari |
 | Artemis Suites Hotel Santorini | Boutique | 15 | Megalochori |
 | Artemis Village Hotel Santorini | 3.0 star rating | 20 | Fira-Karterados |
 | Art Hotel Santorini | 4.0 star rating | 10 | Pyrgos |
 | Aspaki Exclusive Hotel Santorini | 5.0 star rating | 5 | Oia |
 | Astarte Suites Hotel Santorini | 5.0 star rating | 11 | Akrotiri |