 | Best Western Of Walterboro Hotel Walterboro - SC | 3.0 star rating | 106 | Walterboro |
 | Best Western Plus Hardeeville Inn & Suites Hotel Walterboro - SC | 3.0 star rating | 62 | Hardeeville |
| Comfort Inn & Suites Hotel Walterboro - SC | 3.0 star rating | 96 | Walterboro |
| Days Inn Hardeeville Interstate Highway 95 State L Hotel Walterboro - SC | 2.0 star rating | 107 | Hardeeville |
 | Days Inn Walterboro Hotel Walterboro - SC | 3.0 star rating | 61 | Walterboro |
| Econo Lodge Hotel Walterboro - SC | 3.0 star rating | 84 | Yemassee |
| Econo Lodge Hotel Walterboro - SC | 3.0 star rating | 39 | Walterboro |
| Hampton Inn Suites Walterboro Hotel Walterboro - SC | 2.0 star rating | | Walterboro |
 | Hampton Inn Walterboro Hotel Walterboro - SC | 3.0 star rating | 78 | Walterboro |
| Holiday Inn Express and Suites Hardeeville Hilton Hotel Walterboro - SC | 3.0 star rating | | Hardeeville |
| Holiday Inn Express and Suites Walterboro I 95 Hotel Walterboro - SC | 3.0 star rating | | Walterboro |
| Holiday Inn Express Hotel & Suites Hardeeville - H Walterboro - SC | 3.0 star rating | | Hardeeville |
 | Knights Inn Hardeeville Hotel Walterboro - SC | 3.0 star rating | 95 | Hardeeville |
 | Knights Inn Point South Yemassee Hotel Walterboro - SC | 3.0 star rating | 70 | Yemassee |
 | Microtel Inn & Suites Walterboro Hotel Walterboro - SC | 3.0 star rating | 67 | Walterboro |
| Quality Inn & Suites Hotel Walterboro - SC | 3.0 star rating | 84 | Walterboro |
| Quality Inn & Suites Hotel Walterboro - SC | 3.0 star rating | 99 | Hardeeville |
| Ramada Walterboro Hotel Walterboro - SC | 3.0 star rating | 101 | Walterboro |
| Red Roof Inn Hardeeville Hotel Walterboro - SC | 3.0 star rating | 97 | Hardeeville |
 | Rodeway Inn Hotel Walterboro - SC | 2.0 star rating | 72 | Walterboro |
| Rodeway Inn Hotel Walterboro - SC | Without Official Category | | Yemassee |
| Sleep Inn Hotel Walterboro - SC | 3.0 star rating | 75 | Hardeeville |
| Sleep Inn Hotel Walterboro - SC | 3.0 star rating | 56 | Walterboro |
 | Super 8 Hardeeville Hotel Walterboro - SC | 2.0 star rating | 95 | Hardeeville |
 | Super 8 Motel - Walterboro Hotel Walterboro - SC | 3.0 star rating | 45 | Walterboro |