 | Hotel Tyl Prague | 4.0 star rating | 33 | Nove Mesto |
 | Ibis Praha Wenceslas Square Hotel Prague | 3.0 star rating | 181 | Nove Mesto |
| La Ballerina Hotel Prague | 5.0 star rating | 31 | Nove Mesto |
 | Legie Hotel Prague | 3.0 star rating | 51 | Nove Mesto |
 | Le Palais Art Hotel Prague | 5.0 star rating | 72 | Nove Mesto |
| Louren Hotel Prague | 3.0 star rating | 27 | Nove Mesto |
 | Mamaison Residence Belgicka Prague Hotel | 4.0 star rating | 30 | Nove Mesto |
 | Marriott Executive Apartments Hotel Prague | 4.0 star rating | 53 | Nove Mesto |
| MH Apartments Central Prague Hotel | 4.0 star rating | 24 | Nove Mesto |
| Miss Sophie's Hotel Prague | Aparthotel 4* | 35 | Nove Mesto |
| Mosaic House Hotel Prague | 4.0 star rating | 90 | Nove Mesto |
 | Novotel Praha Wenceslas Square Hotel Prague | 4.0 star rating | 146 | Nove Mesto |
 | Occidental Wilson Praha Hotel Prague | 5.0 star rating | 53 | Nove Mesto |
 | Old Time Hotel Prague | 3.0 star rating | 13 | Nove Mesto |
 | Old Town Residence Apartments Hotel Prague | 3.0 star rating | 5 | Nove Mesto |
 | Park Inn Hotel Prague | 4.0 star rating | 210 | Nove Mesto |
 | Praga 1 Hotel Prague | 4.0 star rating | 31 | Nove Mesto |
 | Prague Centre Plaza Hotel | 3.0 star rating | 94 | Nove Mesto |
 | Prague Centre Superior Hotel | 3.0 star rating | 67 | Nove Mesto |
 | Pure White Hotel Prague | 4.0 star rating | 37 | Nove Mesto |
 | Purpur Aparthotel Hotel Prague | 3.0 star rating | 22 | Nove Mesto |
| Residence Jecna Hotel Prague | 4.0 star rating | 8 | Nove Mesto |
 | Residence River View Hotel Prague | Aparthotel 3* | 12 | Nove Mesto |
 | Rezidence Vitkova Hotel Prague | 3.0 star rating | 17 | Nove Mesto |
| Royal Court Apartments Hotel Prague | 3.0 star rating | 20 | Nove Mesto |
 | Royal Court Hotel Prague | 3.0 star rating | 44 | Nove Mesto |
| Royal Plaza Hotel Prague | 3.0 star rating | 32 | Nove Mesto |
 | San Marco Hotel Prague | 3.0 star rating | 19 | Nove Mesto |
 | Select Hotel Prague | 3.0 star rating | 25 | Nove Mesto |
 | Sheraton Prague Charles Square Hotel | 5.0 star rating | 160 | Nove Mesto |
 | Sofia Hotel Prague | 3.0 star rating | 19 | Nove Mesto |
| St. George Hotel Prague | 3.0 star rating | 57 | Nove Mesto |
 | Suite Home Prague Hotel | 4.0 star rating | 28 | Nove Mesto |
| Sunrise Hotel Prague | 3.0 star rating | | Nove Mesto |
 | Union Hotel Prague | 4.0 star rating | 57 | Nove Mesto |