 | St Regis Osaka Hotel | 5.0 star rating | 160 | Osaka |
 | Sunroute Osaka Namba Hotel | 3.0 star rating | 698 | Osaka |
 | Swissotel Nankai Osaka Hotel | 5.0 star rating | 548 | Osaka |
 | Tennoji Miyako Hotel Osaka | 4.0 star rating | 200 | Osaka |
| The Hotel North Osaka | 3.0 star rating | | Osaka |
 | Toko City Hotel Umeda Osaka | 3.0 star rating | 300 | Osaka |
| Toyoko Inn Hankyu Juso-eki Nishiguchi Hotel Osaka | 3.0 star rating | 275 | Osaka |
| Toyoko Inn Osaka Itami Kuko Hotel | 3.0 star rating | 296 | Osaka |
 | Toyoko Inn Osaka Jr Noda Ekimae Hotel | 3.0 star rating | 215 | Osaka |
| Toyoko Inn Osaka Nanba Hotel | 3.0 star rating | 142 | Osaka |
| Toyoko Inn Osaka Senba Hotel | 3.0 star rating | | Osaka |
| Toyoko Inn Osaka Taniyon Kousaten Hotel | 3.0 star rating | 195 | Osaka |
| Toyoko Inn Osaka Tsuruhashi Ekimae Hotel | 3.0 star rating | 119 | Osaka |
 | Toyoko Inn Osaka Umeda Higashi Hotel | 3.0 star rating | 230 | Osaka |
| Toyoko Inn Osaka Umeda Nakatsu Hotel | 3.0 star rating | | Osaka |
| Toyoko Inn Sakaisuji-Honmachi Cyuou-Oodori Hotel Osaka | 3.0 star rating | 188 | Osaka |
| Toyoko Inn Shin-Osaka Chuo-Guchi Honkan Hotel | 3.0 star rating | | Osaka |
| Toyoko Inn Shin-Osaka Chuo-Guchi Shinkan Hotel | 3.0 star rating | | Osaka |
| Toyoko Inn Shin-Osaka-Eki Higashi-Guchi Hotel | 3.0 star rating | 128 | Osaka |
| Toyoko Inn Shinsaibashi Nishi Hotel Osaka | 3.0 star rating | 143 | Osaka |
| Toyoko Inn Tenmabashi Otemae Hotel Osaka | 3.0 star rating | 119 | Osaka |
 | Toyoko Inn Yodoyabashi-Eki Minami Hotel Osaka | 3.0 star rating | 376 | Osaka |
| Trusty Shinsaibashi Hotel Osaka | 3.0 star rating | 211 | Osaka |
 | Umeda OS Hotel Osaka | 3.0 star rating | 283 | Osaka |
| Universal Port Hotel Osaka | 4.0 star rating | 600 | Osaka |
| ViaInn Shin Osaka Hotel | 3.0 star rating | | Osaka |
| Viainn Shinsaibashi Nagahoridori Hotel Osaka | 4.0 star rating | | Osaka |
 | Villa Fontaine Shinsaibashi Hotel Osaka | 4.0 star rating | 90 | Osaka |
 | Weekly Green In Namba Hotel Osaka | 2.0 star rating | 5 | Osaka |
 | Westin Osaka Hotel | 5.0 star rating | 304 | Osaka |
 | Wing International Shinosaka Hotel Osaka | 3.0 star rating | 110 | Osaka |
 | Yamatoya Honten Hotel Osaka | 3.0 star rating | 39 | Osaka |
 | Yumoto Hananoi Super Hotel Natural Hot Springs Osaka | 2.0 star rating | 445 | Osaka |