 | Baymont Inn & Suites Seabrook Kemah Hotel Houston - TX | 3.0 star rating | 49 | Space Center Area |
 | Best Western Plus Seabrook Suites Hotel Houston - TX | 3.0 star rating | 86 | Space Center Area |
| Boardwalk Inn Hotel Houston - TX | 3.0 star rating | | Space Center Area |
| Candlewood Suites League City Hotel Houston - TX | 3.0 star rating | 83 | Space Center Area |
 | Comfort Suites (Webster) Hotel Houston - TX | 3.0 star rating | 58 | Space Center Area |
| Courtyard Houston NASA/Clear Lake Hotel Houston - TX | 3.0 star rating | 124 | Space Center Area |
| Days Inn Kemah Hotel Houston - TX | 3.0 star rating | 42 | Space Center Area |
| Days Inn Kemah Hotel Houston - TX | 3.0 star rating | 43 | Space Center Area |
 | Days Inn & Suites Webster NASA - Clear Lake - Hous Hotel Houston - TX | 3.0 star rating | 63 | Space Center Area |
 | Hampton Inn Seabrook/Kemah Hotel Houston - TX | 3.0 star rating | 70 | Space Center Area |
 | Hampton Inn & Suites Houston Clear Lake Nasa Area Hotel Houston - TX | 3.0 star rating | 108 | Space Center Area |
 | Hampton Inn & Suites Houston League City Hotel Houston - TX | 3.0 star rating | 81 | Space Center Area |
 | Hilton Garden Inn Houston/Clear Lake NASA Hotel Houston - TX | 3.0 star rating | 126 | Space Center Area |
| Holiday Inn Express & Suites Houston Space Center Hotel Houston - TX | 3.0 star rating | 101 | Space Center Area |
| Holiday Inn Houston-Webster Hotel Houston - TX | 3.0 star rating | 109 | Space Center Area |
| Holiday Inn Kemah (Near Boardwalk) Hotel Houston - TX | 3.0 star rating | 128 | Space Center Area |
 | La Quinta Inn & Suites Houston NASA Hotel Houston - TX | 3.0 star rating | 77 | Space Center Area |
 | Microtel Inn & Suites Nasa Hotel Houston - TX | 3.0 star rating | 54 | Space Center Area |
 | Quality Inn & Suites Yacht Club Basin Hotel Houston - TX | 2.0 star rating | 60 | Space Center Area |
| SpringHill Suites Houston NASA/Seabrook Hotel Houston - TX | 3.0 star rating | 88 | Space Center Area |
| SpringHill Suites Houston NASA/Webster Hotel Houston - TX | 3.0 star rating | 121 | Space Center Area |
| Staybridge Suites Houston Nasa/Clear Lake Hotel Houston - TX | 3.0 star rating | 112 | Space Center Area |
| Super 8 League City/Kemah Area Hotel Houston - TX | 3.0 star rating | 43 | Space Center Area |
| Super 8 Motel - Houston/Webster/Nasa Area Hotel Houston - TX | 3.0 star rating | 60 | Space Center Area |