 | AMERICAS BEST VALUE INN HOUSTON Hotel Houston - TX | 3.0 star rating | 45 | Medical Centre |
 | Baymont Inn & Suites Houston I-45 North Hotel Houston - TX | 3.0 star rating | 135 | Medical Centre |
| Best Way Inn Houston Hotel Houston - TX | 3.0 star rating | 43 | Medical Centre |
 | Best Western Plaza Hotel & Suites At Medical Cntr. Houston - TX | 3.0 star rating | 125 | Medical Centre |
| Candlewood Suites Houston Medical Center Hotel Houston - TX | 3.0 star rating | 80 | Medical Centre |
 | Comfort Suites Hotel Houston - TX | 3.0 star rating | 69 | Medical Centre |
 | Comfort Suites - Near the Galleria Hotel Houston - TX | 3.0 star rating | 61 | Medical Centre |
 | Coutyard by Marriot-Medical Center Hotel Houston - TX | 3.0 star rating | 197 | Medical Centre |
| Crossland Economy Studios - Houston - West Oaks Hotel Houston - TX | 3.0 star rating | 145 | Medical Centre |
 | Days Inn and Suites & Suites Houston North/Aldine Hotel Houston - TX | 3.0 star rating | 85 | Medical Centre |
 | Days Inn & Suites Houston Hotel Houston - TX | 3.0 star rating | 38 | Medical Centre |
 | Days Inn & Suites Houston North-Spring Hotel Houston - TX | 3.0 star rating | 45 | Medical Centre |
 | Fairfield Inn Houston 1-10 Eeast Hotel Houston - TX | 3.0 star rating | | Medical Centre |
 | Hampton Inn & Suites Houston-Medical Ctr-Reliant Hotel Houston - TX | 3.0 star rating | 120 | Medical Centre |
 | Hilton Houston Plaza/Medical Center Hotel Houston - TX | 4.0 star rating | 186 | Medical Centre |
 | HOLIDAY INN HOUSTON S - NRG AREA - MED CTR Hotel Houston - TX | 4.0 star rating | 238 | Medical Centre |
| Holiday Inn & Suites Houston West - Westway Park Hotel Houston - TX | 3.0 star rating | 113 | Medical Centre |
| Houston Marriott at the Texas Medical Center Hotel Houston - TX | 3.0 star rating | 395 | Medical Centre |
 | Howard Johnson Express Inn - Houston Hotel Houston - TX | 3.0 star rating | 29 | Medical Centre |
 | MainStay Suites Texas Medical Center/Reliant Park Hotel Houston - TX | 3.0 star rating | 89 | Medical Centre |
 | Quality Inn & Suites Hotel Houston - TX | 2.0 star rating | 81 | Medical Centre |
 | Quality Inn & Suites Reliant Park Medical Center Hotel Houston - TX | 2.0 star rating | 106 | Medical Centre |
 | Quality Inn & Suites West - Energy Corridor Hotel Houston - TX | 2.0 star rating | 63 | Medical Centre |
 | Quality Suites North Hotel Houston - TX | 3.0 star rating | 51 | Medical Centre |
 | Residence Inn by Marriott Houston Hotel Houston - TX | 3.0 star rating | 287 | Medical Centre |
 | Rodeway Inn & Suites Medical Center Hotel Houston - TX | 2.0 star rating | 33 | Medical Centre |
| Scottish Inns Westcott Street Hotel Houston - TX | 3.0 star rating | 19 | Medical Centre |
 | Sleep Inn & Suites Hotel Houston - TX | 2.0 star rating | 41 | Medical Centre |
| SpringHill Suites Houston Medical Center Hotel Houston - TX | 3.0 star rating | 190 | Medical Centre |
 | Super 8 Houston I 45 Hotel Houston - TX | 3.0 star rating | 40 | Medical Centre |
| Super 8 Motel - Houston/Dtwn/I-610 Hotel Houston - TX | 3.0 star rating | 50 | Medical Centre |
 | Wyndham Houston - Medical Center Hotel and Suites Houston - TX | 3 Keys | 287 | Medical Centre |