 | Diana Park Hotel Florence | 4.0 star rating | 26 | Florence |
 | Dimore la Vecchia Firenze Hotel Florence | 3.0 star rating | | Florence |
 | Diva Hotel Florence | 3.0 star rating | 35 | Florence |
 | DolceVita Apartments Hotel Florence | Vacationals Turistics Houses | | Florence |
 | Domus Florentiae Hotel Florence | 4.0 star rating | 14 | Florence |
 | Donatello Hotel Florence | 3.0 star rating | 34 | Florence |
 | Donatello - Two Bedroom Hotel Florence | Without Official Category | | Lastra a Signa |
 | Dora - Four Bedroom Hotel Florence | Without Official Category | | Barberino Val d'Elsa |
| Duca D'Aosta Hotel Florence | 3.0 star rating | 8 | Florence |
| Duomo Studio & Dante Apartment Hotel Florence | Aparthotel 3* | | Florence |
 | Duomo View Hotel Florence | Bed And Breakfast | 5 | Florence |
 | Eden Hotel Florence | 3.0 star rating | 25 | Florence |
 | Eden Rock Resort Florence | 4.0 star rating | 12 | Florence |
| Embassy Hotel Florence | 4.0 star rating | 38 | Florence |
 | Empoli Hotel Florence | 3.0 star rating | 22 | Lastra a Signa |
| Enza Hotel Florence | 3.0 star rating | 16 | Florence |
 | Erina Hotel Florence | 3.0 star rating | 14 | Florence |
 | Eurhotel Hotel Florence | 3.0 star rating | 39 | Florence |
 | Eurohome Hotel Florence | Bed And Breakfast | 10 | Signa |
 | Eurohome Comfort Apartment Hotel Florence | Apartment 1st Category | 3 | Signa |
 | Europa Signa Hotel Florence | 4.0 star rating | 116 | Signa |
 | Executive Hotel Florence | 3.0 star rating | 48 | Florence |
 | Fattoria Degli Usignoli Hotel Florence | 3.0 star rating | 70 | Florence |
 | Fattoria di Castiglionchio Hotel Florence | Without Official Category | | Fiesole |
| Fattoria di Castiglionchio Hotel Florence | 3.0 star rating | 60 | Incisa Val d'Arno |
 | Fattoria Di Castiglionchio - One Bedroom No.2 Hotel Florence | Without Official Category | | Fiesole |
 | Fattoria Di Castiglionchio - One Bedroom No.3 Hotel Florence | Without Official Category | | Fiesole |
 | Fattoria Di Castiglionchio - One Bedroom No.4 Hotel Florence | Without Official Category | | Fiesole |
 | Fattoria Di Castiglionchio - One Bedroom No.5 Hotel Florence | Without Official Category | | Fiesole |
 | Fattoria Di Castiglionchio - One Bedroom No.6 Hotel Florence | Without Official Category | | Fiesole |
 | Fattoria Di Castiglionchio - Two Bedroom Hotel Florence | Without Official Category | | Fiesole |
 | Fattoria Il Milione Hotel Florence | 3.0 star rating | 31 | Florence |
 | Ferdinando II dei Medici Hotel Florence | 3.0 star rating | 12 | Florence |
 | Fiammetta - Three Bedroom Hotel Florence | Without Official Category | | Lastra a Signa |
| Fienile di Monterinieri Hotel Florence | Without Official Category | | Pratolino |
| Fiorino Hotel Florence | 3.0 star rating | 23 | Florence |
 | Firenze Number Nine Hotel Florence | Standard | 45 | Florence |
 | First Hotel Florence | 4.0 star rating | 127 | Calenzano |
 | Florence Apartments Hotel | Vacationals Turistics Houses | 3 | Florence |
 | Florence Apartments Dante & Beatrice Hotel | Vacationals Turistics Houses | | Florence |
 | Florence Apartments Historical Centre Hotel | Vacationals Turistics Houses | | Florence |
 | Florence Dome Hotel | 3.0 star rating | 10 | Florence |
 | Florence Metropole Hotel | 4.0 star rating | 208 | Florence |
 | Florence Old Bridge B&B Hotel | Bed And Breakfast | 6 | Florence |
 | Florence Persefone Palace Hotel | Pending Category | 12 | Florence |
 | Florence View Apartments Hotel | Aparthotel 4* | 7 | Florence |
 | Focolare - Three Bedroom Hotel Florence | Without Official Category | | Lastra a Signa |
 | Forte 16 Hotel Florence | Apartment 1st Category | 44 | Florence |
 | Four Seasons Hotel Firenze Florence | 5.0 star rating | 116 | Florence |
 | Franchi Hotel Florence | 3.0 star rating | 35 | Florence |