 | Best Western Plus Piedmont Inn & Suites Hotel Spartanburg - Greenville - SC | 3.0 star rating | 60 | Spartanburg |
 | Comfort Inn & Suites Hotel Spartanburg - Greenville - SC | 1 Star | 65 | Spartanburg |
 | Comfort Suites At WestGate Mall Hotel Spartanburg - Greenville - SC | 3.0 star rating | 86 | Spartanburg |
 | Courtyard Spartanburg Hotel Spartanburg - Greenville - SC | 3.0 star rating | 102 | Spartanburg |
 | Days Inn Spartanburg Hotel Spartanburg - Greenville - SC | 3.0 star rating | 42 | Spartanburg |
 | Days Inn Spartanburg, Waccamaw Hotel Spartanburg - Greenville - SC | 3.0 star rating | 82 | Spartanburg |
 | Econo Lodge Hotel Spartanburg - Greenville - SC | 1 Star And A Half | 45 | Spartanburg |
 | Hampton Inn Gaffney Hotel Spartanburg - Greenville - SC | 3.0 star rating | 85 | Spartanburg |
 | Hampton Inn Spartanburg-North I-85 Hotel Spartanburg - Greenville - SC | 3.0 star rating | 86 | Spartanburg |
 | Hampton Inn & Suites Clinton Hotel Spartanburg - Greenville - SC | 3.0 star rating | 100 | Spartanburg |
 | Hampton Inn & Suites Greenville-Spartanburg Hotel Spartanburg - Greenville - SC | 3.0 star rating | 133 | Spartanburg |
 | Hampton Inn & Suites Spartanburg-I-26-Westgate Hotel Spartanburg - Greenville - SC | 3.0 star rating | 126 | Spartanburg |
| Holiday Inn Express Spartanburg-North Hotel Spartanburg - Greenville - SC | 3.0 star rating | 91 | Spartanburg |
| Holiday Inn Express & Suites I-26 & US 29 at Westg Hotel Spartanburg - Greenville - SC | 3.0 star rating | | Spartanburg |
 | Home2 Suites by Hilton Greenville Airport, SC Hotel Spartanburg - Greenville - SC | 3.0 star rating | 102 | Spartanburg |
 | Homewood Suites - Greenville Hotel Spartanburg - Greenville - SC | 3.0 star rating | 110 | Spartanburg |
 | Howard Johnson Inn Spartanburg - Expo Center Hotel Spartanburg - Greenville - SC | 3.0 star rating | 50 | Spartanburg |
 | Microtel Duncan Hotel Spartanburg - Greenville - SC | 3.0 star rating | 59 | Spartanburg |
 | Quality Inn Hotel Spartanburg - Greenville - SC | 2.0 star rating | 83 | Spartanburg |
 | Quality Inn South Hotel Spartanburg - Greenville - SC | 2.0 star rating | 80 | Spartanburg |
| Quality Inn & Suites Hotel Spartanburg - Greenville - SC | 3.0 star rating | 88 | Spartanburg |
 | Rodeway Inn Expo Center Hotel Spartanburg - Greenville - SC | 2.0 star rating | 78 | Spartanburg |
 | Sleep Inn Hotel Spartanburg - Greenville - SC | 4.0 star rating | 60 | Spartanburg |
 | Sleep Inn Hotel Spartanburg - Greenville - SC | 2.0 star rating | 63 | Spartanburg |
| Spartanburg Marriott Hotel Spartanburg - Greenville - SC | 3.0 star rating | 247 | Spartanburg |
 | Super 8 Motel - Spartanburg/I-26 Exit 22 Hotel Spartanburg - Greenville - SC | 3.0 star rating | 63 | Spartanburg |