 | Acuarium Suite Resort Santo Domingo | 3.0 star rating | 33 | Santo Domingo |
 | Antiguo Hotel Europa Santo Domingo | 3.0 star rating | 50 | Santo Domingo |
| Apart Hotel Plaza Colonial Santo Domingo | 3.0 star rating | | Santo Domingo |
| Aurora Del Sol Hotel & Casino Santo Domingo | 3.0 star rating | 50 | Santo Domingo |
 | Barcelo Santo Domingo Hotel | 5.0 star rating | 217 | Santo Domingo |
 | Billini Hotel Santo Domingo | 5.0 star rating | 24 | Santo Domingo |
 | Boutique Hotel Palacio Santo Domingo | 3.0 star rating | 44 | Santo Domingo |
 | Casa Doña Elvira Hotel Santo Domingo | Hostel 1* | 12 | Santo Domingo |
| Casa Naemie Hotel Santo Domingo | 2.0 star rating | | Santo Domingo |
 | Casas Del XVI Hotel Santo Domingo | 5.0 star rating | 7 | Santo Domingo |
 | Catalonia Santo Domingo Hotel | 5.0 star rating | 228 | Santo Domingo |
 | Club Villas Jazmin Hotel Santo Domingo | 3.0 star rating | 26 | Santo Domingo |
 | Conde de Peñalba Hotel Santo Domingo | 3.0 star rating | 20 | Santo Domingo |
 | Courtyard Santo Domingo Hotel | 4.0 star rating | 141 | Santo Domingo |
 | Crowne Plaza Santo Domingo Hotel | 5.0 star rating | 462 | Santo Domingo |
 | Dominican Fiesta Hotel & Casino Santo Domingo | 5.0 star rating | 310 | Santo Domingo |
| Dona Elvira Boutique Hotel Santo Domingo | 3.0 star rating | | Santo Domingo |
| Duque De Wellington Hotel Santo Domingo | 3.0 star rating | | Santo Domingo |
| El Beaterio Casa Museo Hotel Santo Domingo | 3.0 star rating | | Santo Domingo |
 | El Embajador, A Royal Hideaway Hotel Santo Domingo | 5.0 star rating | 298 | Santo Domingo |
 | El Napolitano Hotel & Casino Santo Domingo | 3.0 star rating | 65 | Santo Domingo |
| Embassy Suites by Hilton Santo Domingo Hotel | 5.0 star rating | 150 | Santo Domingo |
 | Frances Santo Domingo MGallery Collection Hotel | 4.0 star rating | 19 | Santo Domingo |
 | Hodelpa Caribe Colonial Hotel Santo Domingo | 4.0 star rating | 49 | Santo Domingo |
 | Hodelpa Nicolas de Ovando Hotel Santo Domingo | 5.0 star rating | 104 | Santo Domingo |
 | Holiday Inn Santo Domingo Hotel | 4.0 star rating | 141 | Santo Domingo |
| Hotel Discovery Santo Domingo | 3.0 star rating | | Santo Domingo |
| Hotel Luis V Santo Domingo | 3.0 star rating | | Santo Domingo |
 | Hotel W&P Santo Domingo Antiguo BQ Santo Domingo | 3.0 star rating | 139 | Santo Domingo |
| Jade Hotel Santo Domingo | 3.0 star rating | 22 | Santo Domingo |
 | JW Marriott Hotel Santo Domingo | 5.0 star rating | 150 | Santo Domingo |
| Los Jensen Hostal Hotel Santo Domingo | 2.0 star rating | | Santo Domingo |
 | LUCA HOTEL Hotel Santo Domingo | 4.0 star rating | 11 | Santo Domingo |
| Luis V Hotel Santo Domingo | 3.0 star rating | | Santo Domingo |
 | Maison Gautreaux Hotel Santo Domingo | 3.0 star rating | 20 | Santo Domingo |
| Mountain View Hotel Santo Domingo | 2.0 star rating | | Santo Domingo |
| Naco Hotel &Casino Santo Domingo | 3.0 star rating | 209 | Santo Domingo |
 | Novus Plaza Hodelpa Hotel Santo Domingo | 3.0 star rating | 96 | Santo Domingo |
 | Paradise Beach Club by VRC Hotel Santo Domingo | 3.0 star rating | | Santo Domingo |
| Plaza Del Sol Apart Hotel Santo Domingo | 3.0 star rating | | Santo Domingo |
 | Plaza Florida Suites Hotel Santo Domingo | 3.0 star rating | 64 | Santo Domingo |
 | Quality Hotel Real Aeropuerto Santo Domingo | 4.0 star rating | 124 | Santo Domingo |
 | Radisson Santo Domingo Hotel | 4.0 star rating | 175 | Santo Domingo |
 | Ramada Santo Domingo Princess Hotel | 3.0 star rating | 90 | Santo Domingo |
 | Real Intercontinental Santo Domingo Hotel | 5.0 star rating | 227 | Santo Domingo |
 | Reina Del Mar Hotel Santo Domingo | 3.0 star rating | 4 | Santo Domingo |
 | Renaissance Santo Domingo Jaragua Hotel & Casino | 5.0 star rating | 300 | Santo Domingo |
| Rig Hotel Boutique Puerto Malecon Santo Domingo | 3.0 star rating | | Santo Domingo |
 | Sheraton Santo Domingo Hotel | 5.0 star rating | 248 | Santo Domingo |
 | Sosua Bay Resort Santo Domingo | 3.0 star rating | 144 | Santo Domingo |