 | Sarmiento Suites Hotel Buenos Aires | 3.0 star rating | 38 | Downtown |
 | Sarum Hotel Buenos Aires | 3.0 star rating | 51 | Belgrano |
 | Savoy Hotel Buenos Aires | 4.0 star rating | 164 | Downtown |
 | Scala Hotel Buenos Aires | 4.0 star rating | 143 | Downtown |
 | Serena Buenos Aires Hotel | 3.0 star rating | 34 | Downtown |
 | SF Suites Hotel Buenos Aires | Aparthotel 4* | 23 | Downtown |
 | Sheraton Buenos Aires Hotel & Convention Center | 5.0 star rating | 739 | Downtown |
 | Sheraton Libertador Hotel Buenos Aires | 5.0 star rating | 200 | Downtown |
| Sheraton Pilar Hotel Convention Center Buenos Aires | 5.0 star rating | | Pilar |
 | Siena Hotel Buenos Aires | 1 Star | 34 | Downtown |
 | Sileo Hotel Buenos Aires | 4.0 star rating | 24 | Downtown |
| Simple & Charming Bed And Breakfast Inn Hotel Buenos Aires | Boutique | 5 | Palermo |
 | Sofitel Buenos Aires Hotel | 5.0 star rating | 140 | Downtown |
 | Sofitel La Reserva Cardales Hotel Buenos Aires | 5.0 star rating | 159 | Campana |
 | Soho Point Palermo Hotel Buenos Aires | 3.0 star rating | 24 | Palermo |
 | Solar Soler Bed & Breakfast Hotel Buenos Aires | 3.0 star rating | 9 | Palermo |
| Sol Montserrat Hotel Buenos Aires | 3.0 star rating | 16 | San Telmo |
| Splendid Hotel Buenos Aires | 3.0 star rating | 50 | Downtown |
 | Studio Pueyrredon by Temporary Apartments Hotel Buenos Aires | 4.0 star rating | 18 | Downtown |
| Sudamerika Hostel & Suites Centro Hotel Buenos Aires | 3.0 star rating | 35 | Downtown |
 | Sunlight Recoleta Apartments & Suites Hotel Buenos Aires | Superior 3* | 10 | Downtown |
 | Super Resort Buenos Aires | Aparthotel 2* | 48 | Downtown |
 | Sures Belgrano Suites Hotel Buenos Aires | Aparthotel 4* | 36 | Belgrano |
| Susana Just B and B Hotel Buenos Aires | Bed And Breakfast | 5 | Downtown |
 | Tango de Mayo Hotel Buenos Aires | 4.0 star rating | 59 | Downtown |
| Tanguero Boutique Hotel Buenos Aires | 3.0 star rating | 20 | Downtown |
 | Telmho Hotel Boutique Buenos Aires | 3.0 star rating | 9 | Downtown |
 | The Brick Hotel Buenos Aires MGallery by Sofitel | 5.0 star rating | 175 | Downtown |
| The Loft Hotel Buenos Aires | 2.0 star rating | | Downtown |
 | Top Rentals Hotel Buenos Aires | Without Official Category | 81 | Downtown |
 | Tres 65 Concept Buenos Aires Hotel | 4.0 star rating | 37 | Downtown |
 | Tres Sargentos Hotel Buenos Aires | 2.0 star rating | 57 | Downtown |
 | Tribeca Buenos Aires Apart Hotel | Aparthotel 4* | 40 | Downtown |
 | Tribeca Studios Hotel Buenos Aires | Aparthotel 3* | 27 | Almagro |
 | Tritone Hotel Buenos Aires | 3.0 star rating | 53 | Downtown |
 | Tryp Buenos Aires Hotel | 4.0 star rating | 60 | Downtown |
 | Tucuman Palace Hotel Buenos Aires | 2.0 star rating | 57 | Downtown |
 | Two Hotel Buenos Aires | 3.0 star rating | 147 | Downtown |
 | Ulises Recoleta Hotel Buenos Aires | Boutique | 26 | Downtown |
 | Ultra Hotel Buenos Aires | Boutique | 20 | Palermo |
 | Unique Art Elegance Hotel Buenos Aires | 4.0 star rating | 43 | Downtown |
 | Unique Art Madero Hotel Buenos Aires | 4.0 star rating | 89 | San Telmo |
 | Unique Executive Central Hotel Buenos Aires | 4.0 star rating | 70 | Downtown |
 | Unique Executive Chateau Hotel Buenos Aires | 4.0 star rating | 63 | Downtown |
 | Unique Luxury Park Plaza Hotel Buenos Aires | 4.0 star rating | 54 | Downtown |
 | Unique Palacio Chic Hotel Buenos Aires | 4.0 star rating | 45 | Downtown |
 | Unique Palacio San Telmo Hotel Buenos Aires | 4.0 star rating | 45 | San Telmo |
| Uno Buenos Aires Suites Hotel | 3.0 star rating | 80 | Downtown |
 | Urbanica Suites Hotel Buenos Aires | Aparthotel 4* | 24 | Belgrano |
 | Urbanica The Libertador Hotel Buenos Aires | 4.0 star rating | 55 | Downtown |