 | Sileo Hotel Buenos Aires | 4.0 star rating | 24 | Downtown |
 | Sofitel Buenos Aires Hotel | 5.0 star rating | 140 | Downtown |
| Splendid Hotel Buenos Aires | 3.0 star rating | 50 | Downtown |
 | Studio Pueyrredon by Temporary Apartments Hotel Buenos Aires | 4.0 star rating | 18 | Downtown |
| Sudamerika Hostel & Suites Centro Hotel Buenos Aires | 3.0 star rating | 35 | Downtown |
 | Sunlight Recoleta Apartments & Suites Hotel Buenos Aires | Superior 3* | 10 | Downtown |
 | Super Resort Buenos Aires | Aparthotel 2* | 48 | Downtown |
| Susana Just B and B Hotel Buenos Aires | Bed And Breakfast | 5 | Downtown |
 | Tango de Mayo Hotel Buenos Aires | 4.0 star rating | 59 | Downtown |
| Tanguero Boutique Hotel Buenos Aires | 3.0 star rating | 20 | Downtown |
 | Telmho Hotel Boutique Buenos Aires | 3.0 star rating | 9 | Downtown |
 | The Brick Hotel Buenos Aires MGallery by Sofitel | 5.0 star rating | 175 | Downtown |
| The Loft Hotel Buenos Aires | 2.0 star rating | | Downtown |
 | Top Rentals Hotel Buenos Aires | Without Official Category | 81 | Downtown |
 | Tres 65 Concept Buenos Aires Hotel | 4.0 star rating | 37 | Downtown |
 | Tres Sargentos Hotel Buenos Aires | 2.0 star rating | 57 | Downtown |
 | Tribeca Buenos Aires Apart Hotel | Aparthotel 4* | 40 | Downtown |
 | Tritone Hotel Buenos Aires | 3.0 star rating | 53 | Downtown |
 | Tryp Buenos Aires Hotel | 4.0 star rating | 60 | Downtown |
 | Tucuman Palace Hotel Buenos Aires | 2.0 star rating | 57 | Downtown |
 | Two Hotel Buenos Aires | 3.0 star rating | 147 | Downtown |
 | Ulises Recoleta Hotel Buenos Aires | Boutique | 26 | Downtown |
 | Unique Art Elegance Hotel Buenos Aires | 4.0 star rating | 43 | Downtown |
 | Unique Executive Central Hotel Buenos Aires | 4.0 star rating | 70 | Downtown |
 | Unique Executive Chateau Hotel Buenos Aires | 4.0 star rating | 63 | Downtown |
 | Unique Luxury Park Plaza Hotel Buenos Aires | 4.0 star rating | 54 | Downtown |
 | Unique Palacio Chic Hotel Buenos Aires | 4.0 star rating | 45 | Downtown |
| Uno Buenos Aires Suites Hotel | 3.0 star rating | 80 | Downtown |
 | Urbanica The Libertador Hotel Buenos Aires | 4.0 star rating | 55 | Downtown |
 | Urban Suites Recoleta Boutique Hotel Buenos Aires | 4.0 star rating | 34 | Downtown |
 | Uthgra De las Luces Hotel Buenos Aires | 3.0 star rating | 52 | Downtown |
 | Viamonte Buenos Aires Apart Hotel | Aparthotel 3* | 44 | Downtown |
 | Viasui Hotel Buenos Aires | 3.0 star rating | 58 | Downtown |
| Victory Hotel Buenos Aires | 3.0 star rating | 90 | Downtown |
 | Vista Sol Hotel Buenos Aires | 4.0 star rating | 83 | Downtown |
 | Waldorf Hotel Buenos Aires | 3.0 star rating | 118 | Downtown |
 | Wilton Hotel Buenos Aires | 4.0 star rating | 97 | Downtown |
 | Zentra Hotel Buenos Aires | 3.0 star rating | 32 | Downtown |